Altered Active Site Flexibility and a Structural Metal-binding Site in Eukaryotic dUTPase
نویسندگان
چکیده
منابع مشابه
Crystal structure of dUTPase from equine infectious anaemia virus; active site metal binding in a substrate analogue complex.
The X-ray structures of dUTPase from equine infectious anaemia virus (EIAV) in unliganded and complexed forms have been determined to 1.9 and 2.0 A resolution, respectively. The structures were solved by molecular replacement using Escherichia coli dUTPase as search model. The exploitation of a relatively novel refinement approach for the initial model, combining maximum likelihood refinement w...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2004
ISSN: 0021-9258
DOI: 10.1074/jbc.m313643200